All mattresses should have protection. It will give you optimal return on your mattress investment plus insure your mattress warranty. Your guests will appreciate the cleanliness & protection of a cover when using the bed. It is important to have zippered waterproof encasements for mattress and box spring for protection from dust mites, bedbugs & protection against spills, etc. These covers should be zippered (which will not need removing). You should then protect your mattress with a mattress pad for comfort. These can be washed and dried before dressing the bed for next 
use. It would be wise to have a few extra mattress pads for emergency situations.
Vacuuming is the only recommended cleaning method. If covered with a waterproof mattress cover, you should not have any stains directly on the mattress. If there is liquid on the mattress, we recommend using a towel to blot the liquid. Apply gentle pressure to absorb the liquid. Do not press the liquid into the mattress. If you must clean a stain, use mild soap with cold water and apply lightly! Don’t ever soak a mattress or foundation and don’t use dry cleaning fluid of any type on your mattress — these chemicals could damage some of the comfort and upholstery materials.
For general care, always flip and rotate the mattress. A two-sided mattress should be flipped and rotated regularly. Mattress can be flipped in Summer & again in Winter. You could then do the rotating of the mattress in Spring & Fall. Single sided mattresses should also be rotated-although you do not flip, obviously. Again, you can choose time of year and schedule all flips and rotations on a calendar.
You should also rotate your box spring once a year.
Always use a bed frame with a rigid center support that supports the head, foot, sides and center of the mattress and box spring. If using bed slats with a mattress and box spring, use at least three rigid, no-slag slats.
InnStyle can supply your Inn or Bed and Breakfast with mattresses at wholesale pricing. Contact your InnStyle representative or call Toll Free: 1-800-877-INNS (4667) to receive Personal Service at Wholesale Pricing.